The PHGDH Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to 3PGDH, PDG, and PHGDH. This antibody recognizes Human, and Mouse antigen. The PHGDH Antibody has been validated for the following applications: Western Blot.
Description
This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known